SCIENTIFIC WORKSHOPS
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Saturday July 12 |
Sunday July 13 |
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W101: Potpourri of Interesting Gynecological and Non-Gynecological Cytology Cases
W102: Interepretation of the Non-neoplastic Mucosal Biopsies of the Gastro-intestinal Tract
W103: Hematopathology for the Surgical Pathologist – Potential Diagnostic Pitfalls
W104: Pathology of Diffuse Non-Neoplastic Lung Disease
W105: Breast Pathology: Current Challenges and Future Directions
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W301: Glandular Lesions of the Uterine Cervix: Cytologic and Histopathologic Features
W302: Controversies in the Diagnosis and Classification of Ovarian Tumors
W303: Diagnostic Challenges in Surgical Neuropathology
W304: Recent Developments in the Surgical Pathology of Salivary Glands
W305: Diagnostic Immunohistochemistry: A Practical Approach to Common Problems
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W201: Fine Needle Aspiration Cytology of the Thyroid
W202: Recent Advances in the Diagnosis and Classification of Kidney and Urinary Bladder Tumours
W203: Benign Paediatric Haematopathology: Pitfalls and Pearls
W204: The Morphological Basis of Sudden Cardiac Death
W205: The Role of the Pathologist in Organ Transplantation
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W401: Surgical Pathology Microscopy Workshop: A Medley of GI, GU, Breast, Head and Neck
W402: Cutaneous Melanocytic Lesions
W403: Forensic Pathology and the Miscarriage of Justice
W404: Standardized Handling and Reporting of Oncologic Pathology: Esophageal, Gastric and Colorectal Cancer Resection Specimens
W405: Diagnostic Approach to Selected Categories in Soft Tissue Tumors with Emphasis on Current Concepts; Interpretation of Tru-cut Biopsies and Various Immunohistochemical and Molecular Diagnostic Tests
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| SATURDAY JULY 12 MORNING WORKSHOPS |
W101: Potpourri of Interesting Gynecological and Non-Gynecological Cytology Cases
Shahidul Islam, The Ottawa Hospital at the University of Ottawa, Ottawa, Ontario
Celia E. Marginean, The Ottawa Hospital at the University of Ottawa, Ottawa, Ontario |
The course will include case presentations with digital images. Diagnostic criteria will be addressed in the clinical context. A variety of cases will be discussed to highlight diagnostic pitfalls with cytohistocorrelation. The course will end with discussion on clinical implications of the pathologic diagnosis.
Objectives:
- To recognize architectural patterns and cytomorphologic features to classify lesions;
- To review the differential diagnosis that have overlapping features with cytohistologic correlation;
- To discuss the clinical implications of the pathologic diagnosis.
Click here: Dr. Shahidul Islam biography
Shahidul Islam, MD, PhD
Director of Cytopathology
The Ottawa Hospital at the University of Ottawa
Anatomic Pathology, The Eye Institute
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Click here: Dr. Celia E. Marginean biography
Celia E. Marginean, MD
Staff Anatomic Pathologist, The Ottawa Hospital
Director of Undergraduate Medical Education, University of Ottawa
The Ottawa Hospital at the University of Ottawa
Anatomic Pathology, The Eye Institute
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Format: Individual Microscopes
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W102: Interepretation of the Non-neoplastic Mucosal Biopsies of the Gastro-intestinal Tract
Stefan Urbanski, University of Calgary, Calgary, Alberta |
This course is designed for the pathologists interpreting mucosal biopsies of the GI tract in the secondary/tertiary centers. The material will include archival biopsies with known follow-up. The slides will be projected using digital camera. A handout with decription of the preseted cases will be available to the participants at the time of presentation.
Objectives:
- To provide practical approach to the diagnosis of these biopsies focusing on common diagnostic challanges. The presented cases will include common entities of esophageal, gastric, small and large intestinal mucosa including vermiform appendix;
- To stress the importance of clinical aspects necessary in the correct biopsy interpretation;
- To discuss emerging diagnostic challenges related to the new therapeutic measures.
Click here: Dr. Stefan Urbanski biography
Stefan Urbanski
Dr. Urbanski is a Professor of Pathology and Internal Medicine at the University of Calgary and Calgary Lab Services. He is presently involved primarily in the diagnostic pathology and teaching of gastrointestinal pathology, hepatopathology and pulmonary pathology. He completed his pathology training at the University of Toronto and spent his first few years as a junior pathologist at the Princess Margaret Hospital in Toronto. Dr. Urbanski has been In Calgary since 1984.
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W103: Hematopathology for the Surgical Pathologist – Potential Diagnostic Pitfalls
Catherine Ross, Hamilton Health Sciences, Hamilton, Ontario
Monalisa Sur, Hamilton Health Sciences, Hamilton, Ontario |
Twelve cases, which have significant potential to be missed or misdiagnosed, will be presented within the WHO classification. The emphasis will be on cases which may often be confused with non-hematopoietic neoplasms based on the morphology. In addition, cases in which the appearances and sometimes the ancillary studies can present confusion both in diagnosis and classification will be discussed. The utility of both immunohistochemistry and other studies (flow cytometry and molecular studies) as aids to diagnosis will be highlighted. Examples of newer entities within the WHO classification will be shown and discussed. The cases will have routine H&E stains and full immunohistochemical panel with discussions on the differential diagnosis highlighted points to avoid diagnostic pitfalls.
Objectives:
At the conclusion of this workshop the participant will:
- Have a heightened awareness about selected areas in hematopathology that are prone to diagnostic errors;
- Understand the importance of judicious use of ancillary techniques to avoid the pitfalls;
- Be aware of the current status of lymphoma classification and where the described entities fit in;
- Know when to consider HD neoplasms and variants in the differential diagnosis.
Click here: Dr. Catherine Ross biography
Catherine Ross
Dr. Catherine Ross is an Associate Professor in the Department of Molecular Medicine and Pathology at Hamilton Health Sciences, McMaster University. She is currently Director of the Hematopathology Department which includes cell diagnostics and flow cytometry. She was trained in Hamilton and Toronto and completed her Fellowship in Pathology in 1998. Dr. Ross also completed a Master's in Molecular Virology. Her current interests include Hematopathology and Mechanisms into the effects of new biological agents in Non Hodgkins Lymphoma. She is also involved in undergraduate education in the Degroote School of Medicine, McMaster University.
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Click here: Dr. Monalisa Sur biography
Monalisa Sur
Monalisa Sur was born on the 23rd of September 1967 in Chandigarh, India. She did her undergraduate medical training from Dayanand Medical College in Ludhiana, India. In 1994, she moved to Johannesburg, South Africa where she did her Postgraduate Medical training in Anatomical Pathology. She trained at the University of the Witwatersrand, South African Institute for Medical Research (SAIMR) in Johannesburg. In 1998, she appeared for the Fellowship examinations of the College of Anatomical Pathologists of South Africa. She passed this exam with flying colors and was awarded the F.C.Path (S.A.) Anat. Path and the Coulter medal for outstanding performance at the Fellowship examinations and the James Lear award for the most outstanding resident in laboratory Medicine by the SAIMR. In 1999, Monalisa was awarded the M.Med in Anatomical Pathology by the University of the Witwatersrand, Johannesburg with distinction for her thesis titled “Morphological changes and effect on tumor suppressor gene expression induced by High Dose Rate Intraluminal Brachytherapy of esophageal carcinoma”
Monalisa became a Staff Pathologist in 1999 at the University of the Witwatersrand, South African Institute of Medical Research, Johannesburg. During this period, the lymphoma group involved with the Real classification came to the department of Anatomical Pathology at the University of the Witwatersrand to study cases for comparing and contrasting with the REAL and WHO classifications before implementation of the latter. This proved to be a very useful experience for Monalisa as she was actively involved in the reviewing and classifying these hematopathology cases with the world experts. She continued to publish and teach which resulted in her achieving the rank of a Senior Lecturer at the University of the Witwatersrand in South South Africa. In 2000, Monalisa received the M.R.C.Path in Anatomical Pathology from the Royal College of Pathologists of U.K. This was after she had received the Diploma of the Royal College of Pathology the previous year.
Although the academic and work environment in South Africa was very challenging and satisfying, Monalisa and her husband, a Radiation Oncologist, worried about the safety and future of their daughter. In 2002, Monalisa joined Hamilton Health Sciences as a Staff Pathologist. She received appointment as an Associate Professor of Anatomical Pathology at McMaster University and Fellowship of the Royal College of Physicians and Surgeons of Canada in Anatomical Pathology.
Besides contributing a book chapter, Monalisa has published over 30 journal articles with many more in press or under consideration. She has presented extensively in conferences and meetings over the years. Her interest lies mainly in the field of Hematopathology, with this being her main area of teaching and research in the past few years.
Monalisa became a Canadian citizen in 2006. In February of 2008, she will be awarded the F.R.C.Path by the Royal College of Pathologist of U.K. in recognition of her abilities and contribution to Pathology. Presently Monalisa holds the position of a Staff Pathologist with interest in Hematopathology at Hamilton Health Sciences and an Associate Professor and Program Director of Anatomical Pathology at McMaster University in Hamilton.
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W104: Pathology of Diffuse Non-Neoplastic Lung Disease
John C. English, Vancouver General Hospital, Vancouver, British Columbia |
Diffuse non-neoplastic pulmonary disease often poses diagnostic dilemmas for beginner and experienced pathologist alike. This is due, in part, to the fact that these conditions are not common, or at least are not commonly biopsied, and thus it is difficult to acquire a comfortable understanding of the relevant issues. In addition, the entire population of diffuse lung diseases has inadvertently acquired a complex nomenclature with overlapping descriptive terminologies and etiological classifications.
This workshop is directed at practicing Anatomical and General Pathologists as well as residents in pathology. The central focus of this course will be on the idiopathic interstitial pneumonias with discussion of other conditions that routinely enter the differential diagnosis, including hypersensitivity pneumonitis, collagen vascular-related lung disease, smoking-related interstitial lung disease and lung manifestations of drug toxicity. Acute lung injury will also be addressed in this context, as will the relevant pulmonary eosinophilic disorders. Throughout the discussion, relevant radiological and clinical correlation will be related to pathological manifestations, underscoring the utility of the “team” approach to the diagnosis of diffuse pulmonary disease.
Objectives:
At the conclusion of this workshop the participant will:
- Understand the importance of appropriate specimen handling in the context of diffuse lung disease;
- Be able to develop an overall approach to determining the salient injury / repair patterns that form the basis of a confident diagnosis or differential diagnosis in diffuse pulmonary disease with special reference to the idiopathic interstitial pneumonias (the "IP’s") and secondary forms of interstitial lung disease;
- Understand how patterns of pulmonary inflammation and fibrosis are common to many idiopathic and secondary causes of diffuse lung disease and how these patterns pose difficult diagnostic challenges to the pathologist;
- Understand how knowledge of clinical features and radiological disease patterns can assist the pathologist in making a diagnosis or an appropriate differential diagnosis in a difficult case of diffuse lung disease.
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W105: Breast Pathology: Current Challenges and Future Directions
Susan Done, University Health Network, Toronto, Ontario
Naomi Miller, University Health Network, Toronto, Ontario |
Objectives:
At the conclusion of this workshop the participant will:
- Be aware of issues involved in handling and sampling of breast specimens resected for in situ duct carcinoma and be familiar with a suggested handling method;
- Have been exposed to several examples of important and challenging diagnostic issues in breast pathology through case based examples of core and excision specimens;
- Understand current molecular techniques of diagnostic and research significance in breast pathology.
Click here: Dr. Susan Done biography
Susan Done, MD
Pathologist
University Health Network
Toronto, Ontario
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Click here: Dr. Naomi Miller biography
Naomi Miller, MD
Pathologist
University Health Network
Toronto, Ontario
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| SATURDAY JULY 12 AFTERNOON WORKSHOPS |
W201: Fine Needle Aspiration Cytology of the Thyroid
Manon Auger, McGill University Health Center, Montreal, Quebec
Heather Barwick, McGill University Health Center, Montreal, Quebec |
This workshop includes a comprehensive didactic portion (lasting approximately 1 hr 15 min) followed by a practical glass slide session (lasting approximately 1 hr 45 min), with focus on the demonstration of the spectrum of cytological features/variants of specific benign and malignant thyroid lesions. Emphasis will be placed on the recognition of diagnostic pitfalls and on approaches to resolve differential diagnostic dilemmas. Many examples of cytological mis-diagnoses will be shown, with emphasis put on the illustration of the cytological clues that could have led to the correct diagnoses in most cases. Histologic correlation will be amply illustrated. Diagnostic limitations of thyroid FNAs will be discussed.
A collection of approximately 160 high quality cases will be available during the microscopic session, for each participant to review on his own microscope, to include the lesions discussed in the didactic portion. "Unknown" cases will be provided for self-assessment and reviewed at the conclusion of the workshop. A comprehensive handout will be distributed to each registrant.
Objectives:
At the conclusion of this workshop the participant will be able to:
- Provide an algorithm for the diagnostic interpretation of fine needle aspirates from the thyroid with an emphasis provided on resolution of differential diagnoses;
- Illustrate a wide range of cytological presentations of benign and malignant thyroid lesions;
- Be familiar with diagnostic pitfalls.
Click here: Dr. Manon Auger biography
Manon Auger
Dr. Auger obtained her undergraduate and medical degrees from McGill University in Montreal. She is currently an Associate Professor and Staff Pathologist in the Department of Pathology at McGill University. She is also the Director of the Cytopathology Laboratory at the McGill University Health Centre.
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Click here: Heather Barwick biography
Heather Barwick, B.Sc; R.T.(CSMLS); CT(ASCP)(IAC)
Chief Cytotechologist
Cytopathology Laboratory
McGill University Health Centre
Montréal, Québec
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Format: Individual Microscopes
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W202: Recent Advances in the Diagnosis and Classification of Kidney and Urinary Bladder Tumours
John Srigley, Credit Valley Hospital, Mississauga, Ontario, and McMaster University, Hamilton, Ontario |
Over the last decade tremendous advances have been made in our understanding of neoplasms of the urinary bladder and kidney resulting in new classification schemes published by the World Health Organization (WH0 2004). In this microtutorial glass slide examples will be used to illustrate the classification of flat and papillary urothelial neoplasia. Concepts of urothelial dysplasia, carcinoma in-situ and papillary urothelial neoplasm of low malignant potential will be reviewed. In the renal tumour area, common and uncommon epithelial neoplasms will be highlighted through case examples. In addition to common clear cell and papillary renal carcinomas and oncocytic neoplasms, the new and evolving entities such as translocation-associated carcinoma, mucinous tubular and spindle cell carcinoma and tubular cystic carcinoma will be illustrated. Selected mixed epithelial and stromal tumours will also be shown. For both urinary bladder and kidney, the current grading and TNM staging systems will be reviewed. The use of ancillary technologies such as immunohistochemistry and molecular studies will be discussed.
This workshop will use plenty of glass slide cases and emphasis will be placed on practical clinical pathologic issues. This workshop will be of value to pathology residents and general and anatomical pathologists.
Objectives:
- To review and illustrate the current classification of bladder neoplasia with emphasis on flat and papillary urothelial tumours;
- To review and illustrate the current classification of renal epithelial neoplasms with emphasis on new and evolving entities;
- To discuss current grading and staging (TNM) systems for epithelial tumours of the urinary bladder and kidney;
- To review the usage of ancillary technologies such as immunohistochemistry in the classification of urinary tract tumour.
Click here: Dr. John Srigley biography
John R. Srigley
Dr. John R. Srigley is Head of the Pathology and Laboratory Medicine Program at Cancer Care Ontario. He also represents Cancer Care Ontario on the Cancer Committee of the College of American Pathologists, a group that has developed internationally recognized cancer checklists for synoptic reporting. Dr. Srigley has championed the role of the pathologist as diagnostic oncologist and has been a leader in the standardization of cancer pathology reporting and Her-2 testing in Ontario. He has also worked with the Canadian Partnership Against Cancer (CPAC) to encourage interprovincial initiatives in synoptic pathology and surgery reporting.
Dr. Srigley is a graduate of the Faculty of Medicine, University of Toronto. Following oncologic pathology training at the University of Toronto and MD Anderson Cancer Centre in Houston, Dr. Srigley practiced for twelve years at the Sunnybrook Health Science Centre where he was Director of Surgical Pathology. Currently, he is a staff pathologist at Credit Valley Hospital and Professor in the Department of Pathology and Molecular Medicine at McMaster University. Dr. Srigley is an international consultant and educator in the field of urologic pathology and has contributed over 200 publications to the literature. He is an author of two recent textbooks on the pathology of prostate cancer including the Armed Forces Institute of Pathology Fascicle. Dr. Srigley is also a co-author of the 2004 WHO Blue Book on Pathology and Genetics of Tumours of the Urinary System and Male Genital Organs. His research interests mainly revolve around clinicopathologic and translational studies of urologic tumours.
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W203: Benign Paediatric Haematopathology: Pitfalls and Pearls
Louis D. Wadsworth, BC Children’s Hospital, Vancouver, British Columbia
Jason C. Ford, BC Children’s Hospital, Vancouver, British Columbia |
This workshop is a case-based exploration of interesting and important diagnostic considerations in paediatric laboratory hematology. Many Canadian centres do not have paediatric hematopathologists, and so rely on pathologists with more adult experience to diagnose paediatric cases. The goal of this workshop is to assist these pathologists (and pathologists in training) to develop a diagnostic approach to hematologic conditions which are more common in paediatrics. Recent molecular and other pathogenetic findings will also be reviewed.
Objectives:
At the conclusion of this workshop the participant will:
- Be able to provide a diagnostic approach to paediatric patients with:
- severe anaemia (haemolytic and hemorrhagic);
- hemoglobinopathy and thalassemia;
- coagulopathies;
- congenital and acquired cytopenias;
- Be able to describe how the workup of these conditions in children differs from adults;
- Be able to discuss recent advances in molecular diagnosis in paediatric Hematopathology.
Click here: Dr. Jason Ford and Dr. Louis Wadsworth biographies
Jason Ford and Louis Wadsworth
Dr. Jason Ford and Dr. Louis Wadsworth are Hematopathologists at the BC Children’s Hospital. Dr. Ford is the head of the Division of Hematopathology. Dr. Wadsworth is the former head of Hematopathology as well as the former head of the BCCH Department of Pathology and of PHSA Labs. Dr. Ford is an Assistant Professor in the Faculty of Medicine at the University of British Columbia, and Dr. Wadsworth is Clinical Professor.
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W204: The Morphological Basis of Sudden Cardiac Death
Jagdish Butany, University of Toronto and Toronto General Hospital, Toronto, Ontario |
This case-based course will cover the causes of Sudden Cardiac Death. Starting with an explanation of the term SCD, this course will cover Coronary artery and Non Coronary causes of SCD. The section of Coronary causes will encompass current concepts in Atherosclerosis, basis of Acute Coronary Syndromes and the pathology of treatment of CAD. The section on non-coronary causes of SCD will cover the pathology of myocarditis, pathology of the cardiomyopathies and some of the rarer entities, some seen more frequently in other jurisdictions. Time permitting, the approach to examination of the heart in SCD, and the molecular basis of SCD will be discussed.
Objectives:
At the conclusion of this workshop the participant will:
- Understand the definition and meaning of Sudden Cardiac Death (SCD);
- Appreciate the morphological basis of Coronary artery lesions underlying SCD;
- Appreciate the morphological basis of SCD in Non Ischemic Heart disease.
Click here: Dr. Jagdish Butany biography
Jagdish Butany
Dr. Butany is a physician and a professor in the Department of Laboratory Medicine and Pathobiology, as well as Head of the Division of Anatomical Pathology at the University of Toronto. He is a staff pathologist at the University Health Network/Toronto Medical Laboratories, Head of the division of Clinical Cardiovascular Pathology and Director of Autopsy services at the UHN. He has published over 175 peer reviewed articles on cardiovascular pathology, written several book chapters and presented his research work at international conferences. His major interest is Cardiovscular Pathology and the Pathology of Prosthetic Cardiovascular devices. He is the Co Editor-in-Chief of Cardiovascular Pathology (the official journal of the {International} Society for Cardiovascular Pathology).
Dr. Butany enjoys teaching, and teaches at the undergraduate and postgraduate levels at the Univ. of Toronto medical school as well as in several other faculties at the University of Toronto. He has a major interest in Continuing Medical Education and has organized and spoken at workshops on Cardiovascular topics. He has received several awards for his teaching activities. Prior to being elected Vice President of the CAP, Dr. Butany was the Chair of the Education Committee of the CAP and organized the Saturday and Sunday workshops for the Annual Meetings.
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W205: The Role of the Pathologist in Organ Transplantation
Vina Alexopoulou, McMaster University Medical Centre, Hamilton, Ontario
Laurette Geldenhuys, QEII Health Sciences Centre and Dalhousie University, Halifax, Nova Scotia |
The workshop will cover the basic principles of transplant rejection; the main histologic features of the most common types of kidney transplant rejection; the basic principles of liver and cardiac rejection; the basic principles of therapy for transplant rejection and the pathologic effect that may result; and the most common infectious and neoplastic processes associated with therapy for transplant rejection.
Objectives:
At the conclusion of this workshop the participant will:
- Understand the basic principles of transplant rejection;
- Identify the main features of the most common types of kidney transplant rejection;
- Understand the basic principles of liver and cardiac rejection;
- Understand the basic principles of therapy for transplant rejection and the pathologic effect that may result;
- Identify the most common infectious and neoplastic processes associated with therapy for transplant rejection.
Click here: Dr. Laurette Geldenhuys biography
Laurette Geldenhuys
Laurette Geldenhuys is a nephropathologist at the QEII Health Sciences Centre and Dalhousie University in Halifax, Nova Scotia. She is also Section Head of Cytopathology and has an interest in Gynecological Pathology. She is involved in medical education and the medical humanities.
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| SUNDAY JULY 13 MORNING WORKSHOPS |
W301: Glandular Lesions of the Uterine Cervix: Cytologic and Histopathologic Features
Máire A. Duggan, University of Calgary and Foothills Hospital, Calgary, Alberta |
Selected cases illustrating the cytopathologic and histopathologic features of usual and unusual glandular lesions of the uterine cervix will be presented. A wide range of cases, encompassing neoplastic and non-neoplastic lesions, will be selected. Following 2 didactic presentations by Dr. Duggan, highlighting the pathological features and pitfalls of diagnosis, registrants will have 90 minutes for independent review of the glass slide packets. Dr. Duggan will be present to answer questions and assist with the evaluation of the slides. Registrants will receive a syllabus of the didactic presentations.
Objectives:
At the conclusion of this workshop the participant will:
- Know the key cytopathologic and histopathologic features of usual and unusual glandular lesions of the uterine cervix.
Click here: Dr. Máire A. Duggan biography
Máire A. Duggan
Dr. Duggan obtained her medical degree from University College Cork, Ireland in 1978. Following a residency in Anatomical Pathology and a fellowship in Cytopathology, she accepted a faculty appointment in the Department of Pathology, University of Calgary in 1985. Her areas of expertise and research relate to cytopathology, laboratory quality assurance, cervical cancer screening, and gynecologic pathology.
Dr. Duggan has over 100 publications in the medical literature and has presented her research as well as taught cytopathology and gynecologic pathology workshops at national and international pathology meetings. She is a member of a large number of medical societies, serves as a committee chair/member for some, and is an external reviewer for a number of medical journals and granting agencies. Dr Duggan was the pathologist member of the 2001 New Zealand Cervical Cancer Screening Inquiry. Dr Duggan was head of the cytology section of the Histopathology Department in Foothills Hospital, Calgary from 1986 to 1996 and Clinical Leader of Cytopathology in Calgary Laboratory Services, Calgary from 1996 to 2001. Presently, Dr. Duggan is a Professor in the department of Pathology and Laboratory Medicine at the University of Calgary, a consultant pathologist at Calgary Laboratory Services and a consultant gynecologic pathologist the Tom Baker Cancer Centre, Calgary, Alberta.
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W302: Controversies in the Diagnosis and Classification of Ovarian Tumors
Patricia Shaw, University Health Network, Toronto, Ontario |
Objectives:
Click here: Dr. Patricia Shaw biography
Patricia Shaw, MD
Associate Professor
University Health Network
Toronto, Ontario
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W303: Diagnostic Challenges in Surgical Neuropathology
John Maguire, Vancouver General Hospital, Vancouver, British Columbia
Arie Perry, Washington University School of Medicine, St. Louis, Missouri |
Neuropathology surgical specimens can pose unique diagnostic challenges that can appear intimidating. Treatment decisions based upon the microscopic interpretation of lesions showing similar histologic features can be as varied as antibiotic therapy, irradiation, frontal lobectomy, immunosuppression, or clinical and radiologic monitoring. By following a practical approach demonstrated with 10 different case scenarios, the participant will be able to identify key diagnostic features when faced with challenging neuropathology biopsies. Although the focus will be on CNS tumours, neurologic diseases mimicking tumours will also be discussed. Intraoperative challenges will be reviewed for each case, and the usefulness and limitations of investigative techniques, including immunohistochemistry and molecular genetic studies, will be discussed when applicable. The case scenarios will demonstrate the importance of considering clinical history, age, biopsy site and relevant diagnostic imaging, in association with histologic characteristics, in order to narrow the differential and achieve diagnostic accuracy. Your effective communication will enable the clinician to decide upon the most appropriate therapy.
Targeted audience: Residents, Pathologists in community and tertiary care settings who deal with neurosurgical specimens.
Objectives:
At the conclusion of this workshop the participant will:
- Understand the current WHO classification of tumors of the CNS;
- Through a series of case scenarios, be aware of the importance of considering clinical history, age, biopsy site and relevant diagnostic imaging, in association with histologic characteristics, in order to narrow the differential and achieve diagnostic accuracy;
- Following the identification of key diagnostic features when faced with challenging neuropathology biopsies, learn how to effectively communicate the pathologic diagnosis to the clinician, so that the most appropriate therapy may be determined and initiated;
- Be aware of the usefulness and limitations of investigative techniques, including immunohistochemistry and molecular genetic studies.
Click here: Dr. Arie Perry biography
Arie Perry
Dr. Perry is a Professor of Pathology within the Neuropathology Division at Washington University School of Medicine in St. Louis. He received his MD and AP/CP residency training at the U. Texas Southwestern Medical Center in Dallas, TX, followed by fellowships in Surgical Pathology, Neuropathology, and Molecular Cytogenetics Research at the Mayo Clinic in Rochester, MN. He maintains busy in-house and consultation services focused most heavily on Surgical Neuropathology cases, particularly brain tumors. His research is clinical/translational in nature and focuses on classification, grading, and biomarker development for a wide variety of brain tumor subtypes. He is probably best known for his studies leading to the revised 2000 and 2007 WHO criteria for meningioma grading and his use of molecular diagnostics in gliomas, such as oligodendroglioma and the small cell variant of glioblastoma. He is a frequently invited speaker and also serves as the medical director of the Anatomic Pathology FISH lab at Washington U. and the chief editor of Brain Pathology, the official journal for the International Society of Neuropathology. Dr. Perry has received several teaching awards, no doubt related in part to his unique and fun approach to educating second year medical students by combining his passions for music and medicine in the form of "Neuropathology Songs".
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W304: Recent Developments in the Surgical Pathology of Salivary Glands
Bayardo Perez-Ordonez, University Health Network, Toronto, Ontario
Ilan Weinreb, University Health Network, Toronto, Ontario |
Objectives:
Click here: Dr. Bayardo Perez-Ordonez biography
Bayardo Perez-Ordonez, MD, FRCPC
Director of Head and Neck Pathology
Department of Pathology
University Health Network
Toronto, Ontario
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Click here: Dr. Ilan Weinreb biography
Ilan Weinreb, M.D., FRCPC
Department of Pathology
University Health Network
Toronto, Ontario
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W305: Diagnostic Immunohistochemistry: A Practical Approach to Common Problems
Emina Emilia Torlakovic, Royal University Hospital, University of Saskatchewan, Saskatoon, Saskatchewan
Malcolm Hayes, BC Cancer Agency, Vancouver, British Columbia |
This workshop will provide a summarized update and focus on current immunohistochemical panels in the diagnostic work up of primary undifferentiated tumours and Metastatic adenocarcinomas of unknown primary origin. The workshop will also address problems in use of organic specific markers and specific use of so-called “non-specific” markers. This workshop is intended to help design the strategy for the work up of different cases. Quality control (QC) issues in diagnostic immunohistochemistry, including both intralaboratory and extralaboratory QC will also be addressed.
Objectives:
At the conclusion of this workshop the participant will be able to:
- List what panels of immunohistochemical tests are most recommended and could be efficiently used for initial and more advanced work up of undifferentiated tumours;
- List what panels of immunohistochemical tests are most recommended and could be efficiently used for initial and more advanced work up of metastatic adenocarcinoma of unknown primary origin;
- The participants will learn “secrets that are used by immunohistochemists” which would help them to employ commonly used test for detection of widely spread non-specific antigens in diagnosing specific diseases;
- Distinguish the roles of intralaboratory and extralaboratory QC in diagnostic immunohistochemistry.
Click here: Dr. Malcolm Hayes biography
Malcolm Hayes
Dr. Hayes has been employed at the BC Cancer Agency in Vancouver since 1993 and has a major interest in oncological pathology and cytopathology. He is involved in many different tumour groups including the "Unknown primary" tumour group.
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Click here: Dr. Emina Emilia Torlakovic biography
Emina Emilia Torlakovic
Emina Emilia Torlakovic is an Associate Professor of Pathology at the University of Saskatchewan. She is the Medical Director of the Diagnostic Immunohistochemistry Laboratory at Department of Pathology, Saskatoon Health Region. She is a Diplomate of the American Board of Pathology in Anatomic and Clinical Pathology and Hematopathology. She has previously lectured on Diagnostic Immunohistochemistry in Europe and was the Director of the Diagnostic Immunohistochemistry Seminar (2001) in Oslo, Norway. She was one of the founding members of NordiQC, a Scandinavian Immunohistochemistry Quality Control Organization. She is a chair of the CAP National Standards Committee/Immunohistochemistry. Her research interests are in the area of immunohistochemistry, hematopathology, and gastrointestinal pathology. Her doctoral thesis evaluated biology and diagnostic applications of detection of B-cell transcription factors. She and Dr. Blake Gilks from Vancouver General Hospital, BC, are currently putting efforts to develop a Canadian Immunohistochemistry Quality Control Group (cIQc).
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| SUNDAY JULY 13 AFTERNOON WORKSHOPS |
W401: Surgical Pathology Microscopy Workshop: A Medley of GI, GU, Breast, Head and Neck
Susan Robertson, The Ottawa Hospital, Ottawa, Ontario
Bich Nguyen, The Ottawa Hospital, Ottawa, Ontario
Bernhard Johan Olberg, The Ottawa Hospital, Ottawa, Ontario |
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Objectives:
At the conclusion of this workshop the participant will be able to:
- Summarize key basic light microscopic features of some common more difficult differential diagnosis leading to a differential diagnosis;
- Compare the standard light microscopic features that lead towards one of these;
- Discuss some of the useful tests that can make these differentials easier.
Click here: Dr. Susan J. Robertson biography
Susan J. Robertson
Trained at Ottawa University Medical School and returned there in 1989 after several years in New Brunswick. Specialty interests include the Pathology of Genitourinary, Breast and Medical Renal disease. Dr. Robertson is currently teaching at Ottawa. She is concentrated in genitourinary and medical kidney disease and her current research is predominantly on animal models of Diabetes. She is also the proud mother of three and is still married to their father (35 years and counting).
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Click here: Dr. Bich Nguyen biography
Bich Nguyen
Dr. Bich Nguyen has recently joined the University of Ottawa with the rank of associate professor. At the Anatomical Pathology service of TOH where she is currently practicing, Dr. Nguyen is our designated liver pathologist and head of the gastrointestinal section. She is a graduate from the University of Sherbrooke, trained as a resident with the University of Montreal and did her double fellowship in liver and GI pathology with both Universities of Montreal and Paris VII. She joined the Saint-Luc hospital in Montreal after her two-year fellowship and has practiced liver and gastrointestinal pathology ever since. In the recent years, her main research interests were liver tumours and transplantation-related liver pathology, as well as immune response of the colonic mucosa in irritable bowel syndrome: these are also the subjects of her papers and abstracts. Dr. Nguyen was the program director of the Anatomical Pathology program of the University of Montreal and is currently a member of the Examination Board of the Royal College.
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W402: Cutaneous Melanocytic Lesions
Duane Barber, Calgary Laboratory Services and the University of Calgary, Calgary, Alberta
Andrea Bruecks, Calgary Laboratory Services and the University of Calgary, Calgary, Alberta |
Objectives:
At the conclusion of this workshop the participant will:
- Understand the histology of benign melanocytic lesions that may mimic melanoma;
- Understand the problems with diagnosis of lentigo malgna and nevoid melanoma;
- Understand concepts related to pathology reporting of primary melanoma and sentinel lymph node biopsies.
Click here: Dr. Duane Barber biography
Duane Barber, MD
Clinical Assistant Professor
Calgary Laboratory Services and the University of Calgary
Calgary, Alberta
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Click here: Dr. Andrea Bruecks biography
Andrea Bruecks, MD
Clinical Assistant Professor
Calgary Laboratory Services and the University of Calgary
Calgary, Alberta
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Format: Lecture
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W403: Forensic Pathology and the Miscarriage of Justice
Michael Pollanen, Office of the Chief Coroner – Forensic Pathology Unit, Toronto, Ontario
Matt Bowes, Nova Scotia Medical Examiner Service, Halifax, Nova Scotia |
In this workshop the occurrence of wrongful conviction and miscarriage of justice related to forensic pathology will be explored. The influence of progressive growth of medical knowledge, admissibility and reliability of medical evidence and the pitfalls associated with postmortem artifacts that mimic injuries will be discussed. Cases will be used to illustrate these important issues. A general discussion will be developed using a controversial sample case.
Objectives:
At the conclusion of this workshop the participant will be able to:
- Review the autopsy pitfalls that have contributed to miscarriage of justice;
- Review post-mortem artefacts that mimic injury;
- Explore systemic methods to improve the quality of death investigation to minimize miscarriage of justice.
Click here: Dr. Michael S. Pollanen biography
Michael S. Pollanen
Dr. Michael Sven Pollanen the Chief Forensic Pathologist for the province of Ontario, Canada employed and an Associate Professor of Pathology in the Department of Laboratory Medicine and Pathobiology in the Faculty of Medicine at the University of Toronto. He was awarded a 1995 Gold Medal of the Governor General of Canada and has published widely in pathology.
Dr. Pollanen has consulted for East Timor (United Nations), Kazakhstan, Uzbekistan, Cambodia, Thailand (Indian Ocean Tsunami), Canadian Department of National Defense and was a visiting professional at the International Criminal Court in The Hague. Dr. Pollanen has recently worked in the area of ‘miscarriages of justice and medical evidence’ and testified in the historical appeal of Steven Truscott, about 50 years after his initial conviction. Dr. Pollanen has recently developed an experimental model to study hypostatic neck hemorrhages, a mimick of strangulation. Dr. Pollanen was also involved in the efforts of the Office of the Chief Coroner for the Inquiry into Pediatric Forensic Pathology in Ontario and related matters.
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Click here: Dr. Matt Bowes biography
Matt Bowes
Dr. Matt Bowes obtained his bachelor of science degree at the University of Toronto and is a graduate of the Queen’s University School of Medicine. After completing his anatomical pathology training at Dalhousie University, he traveled to Miami, Florida, where he was a forensic pathology fellow and associate medical examiner in the Miami-Dade County Medical Examiner Department. Heavily influenced by his wife’s deep roots in Atlantic Canada, he returned to Halifax, where he worked as a consultant forensic pathologist and medical examiner in the Nova Scotia Medical Examiner Service. On January 12, 2006, he was appointed Chief Medical Examiner for the Province of Nova Scotia. Dr. Bowes spends his days juggling the responsibilities of father, husband, physician and administrator.
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Format: Lecture
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W404: Standardized Handling and Reporting of Oncologic Pathology: Esophageal, Gastric and Colorectal Cancer Resection Specimens
Mahmoud Khalifa, Sunnybrook Health Sciences Centre and University of Toronto, Toronto, Ontario
Robert Riddell, Mount Sinai Hospital and University of Toronto, Toronto, Ontario
John Srigley, Credit Valley Hospital, Mississauga, Ontario, and McMaster University, Hamilton, Ontario |
This course uses the College of American Pathologists' checklists as basis for standardized reporting. It focuses on the applied anatomy knowledge base that surgical pathologists need to master in order to accurately process and report on these specimens. It goes in depth into the relevant clinical pathologic correlations identifying the surgical and prognostic significance of each of the required parameters.
Objectives:
At the conclusion of this workshop the participant will be able to:
- To review the evidence-based diagnostic parameters which need to be included in a pathology report for colorectal specimens.
- To improve communication within the multidisciplinary team by clarifying definitions and terminology.
- To better understand the anatomic subtleties of reporting the pathologic findings in the polypectomy and colectomy specimens.
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Click here: Professor Mahmoud Khalifa biography
Mahmoud Khalifa
Professor Mahmoud Khalifa obtained his Medical Degree from Ain Shams University in Cairo, Egypt. He also received his Master's Degree and PhD in Pathology from Ain Shams in 1982 and 1986, respectively. He continued his training in pathology as a Fulbright Scholar at the Armed Forces Institute of Pathology in Washington, DC, and then at the University of Maryland and the University of Oklahoma. Dr. Khalifa completed his Fellowships in Surgical Pathology at the George Washington University Medical Center and Georgetown University Hospital in Washington, DC. He then joined the Department of Laboratory Medicine and Pathobiology at the University of Toronto in 1999. Dr. Khalifa is currently a Professor at the Department of Laboratory Medicine and Pathobiology and the Department of Obstetrics and Gynecology at the University of Toronto. He is a pathologist specializing in gynecologic, hepato-pancreato-biliary and gastrointestinal pathology at Sunnybrook Health Sciences Centre. He is the Director of Surgical Pathology and Director of Oncology Quality Assurance Program in the Department of Pathology at Sunnybrook Health Sciences Centre. Dr. Khalifa also serves as a member of various committees for Cancer Care Ontario where he is involved in patient safety and standardized pathology reporting.
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Click here: Dr. John Srigley biography
John R. Srigley
Dr. John R. Srigley is Head of the Pathology and Laboratory Medicine Program at Cancer Care Ontario. He also represents Cancer Care Ontario on the Cancer Committee of the College of American Pathologists, a group that has developed internationally recognized cancer checklists for synoptic reporting. Dr. Srigley has championed the role of the pathologist as diagnostic oncologist and has been a leader in the standardization of cancer pathology reporting and Her-2 testing in Ontario. He has also worked with the Canadian Partnership Against Cancer (CPAC) to encourage interprovincial initiatives in synoptic pathology and surgery reporting.
Dr. Srigley is a graduate of the Faculty of Medicine, University of Toronto. Following oncologic pathology training at the University of Toronto and MD Anderson Cancer Centre in Houston, Dr. Srigley practiced for twelve years at the Sunnybrook Health Science Centre where he was Director of Surgical Pathology. Currently, he is a staff pathologist at Credit Valley Hospital and Professor in the Department of Pathology and Molecular Medicine at McMaster University. Dr. Srigley is an international consultant and educator in the field of urologic pathology and has contributed over 200 publications to the literature. He is an author of two recent textbooks on the pathology of prostate cancer including the Armed Forces Institute of Pathology Fascicle. Dr. Srigley is also a co-author of the 2004 WHO Blue Book on Pathology and Genetics of Tumours of the Urinary System and Male Genital Organs. His research interests mainly revolve around clinicopathologic and translational studies of urologic tumours.
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Format: Lecture
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W405: Diagnostic Approach to Selected Categories in Soft Tissue Tumors with Emphasis on Current Concepts; Interpretation of Tru-cut Biopsies and Various Immunohistochemical and Molecular Diagnostic Tests
Ayoub Nahal, McGill University Health Centre, Montréal, Québec |
This workshop is designed for the practising pathologist who encounters soft tissue tumors in a frequent pattern and also to general pathologists who are less familiar with many difficult soft tissue tumors categories.
The aim is to emphasize, through the discussion of selected cases: 1) The importance of the pattern recognition as an initial step towards formulating a differential diagnosis; 2) The use of smart immunopanels using select a combination of immunostains that provide high sensitivity and specificity according to current literature; 3) The usefulness and the limitation in obtaining additional molecular diagnostic results in selected sarcomas. The workshop will also discuss Myxoid Soft tissue tumors, an ongoing difficult and challenging category, covering their wide range of differential diagnoses from reactive/benign to sarcomatous entities.
Objectives:
At the conclusion of this workshop the participant will:
- Obtain a working knowledge of selected tumors in major soft tissue tumor categories;
- Recognize the importance of the pattern approach to soft tissue tumors ;
- Understand the strength and the limitation of the various ancillary immunohistochemical and molecular diagnostic tests in confirming specific entities;
- Address the handling, interpretation, differential diagnosis and grading of certain soft tissue tumors encountered in Tru-Cut Biopsies.
Click here: Dr. Ayoub Nahal biography
Ayoub Nahal
Dr. Nahal obtained his MD degree from Aleppo University inn Syria and completed his residency at Saint Vincent’s Hospital and Medical Center in New York. He is currently an Assistant Professor at McGill University and a Staff Pathologist at McGill University Health Center, specializing in Musculoskeletal Pathology and Cytopathology.
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Format: Lecture
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CAP Conference Secretariat
Email: cap@eventsmgt.com
Tel: 613.531.9210
Fax: 613.531.0626
4 Cataraqui Street, Suite 310
Kingston, ON K7K 1Z7
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| 59th
Annual Meeting of the Canadian Association of Pathologists |
| ©2008 Events & Management Plus Inc.
• Phone: (613) 531-9210•
Fax: (613) 531-0626• E-Mail:
cap@eventsmgt.com |
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